VetCostCalc

Vaccinations Cost in South Dakota (2026)

Vet costs in South Dakota are 15% below national avg, so vaccinations prices run lower here too. Exact costs depend on your pet's size, age, and which clinic you use. The breakdown below shows what South Dakota clinics charge for vaccinations in 2026, how each line item compares nationally, and practical ways to save. Low-cost clinics and humane societies can cut some of these prices by half or more.

Vaccination Costs in South Dakota

Vaccine Per dose
Dog DHPP (combo) $31
Dog Rabies $18
Bordetella (kennel cough) $18
Leptospirosis $16
Cat FVRCP $25
Cat Rabies $15
FeLV (feline leukemia) $18

Vet Cost by City in South Dakota

City Wellness Exam
Sioux Falls $57
Rapid City $56
Aberdeen $53
Brookings $54

Vaccinations Cost in South Dakota — FAQ

How much do dog vaccinations cost in South Dakota?

Annual dog vaccinations in South Dakota cost $90/year in 2026 — 15% below the national average. Core vaccines (DHPP, rabies) are required; non-core vaccines (bordetella, leptospirosis, Lyme) are given based on lifestyle. Puppy series runs $120–$200 total.

How much do cat vaccinations cost in South Dakota?

Annual cat vaccinations in South Dakota average $70/year in 2026. Core cat vaccines include FVRCP and rabies. Indoor cats need fewer vaccines than outdoor cats. Kitten series typically runs $100–$160 total in South Dakota.

Are there low-cost vaccination clinics in South Dakota?

Yes — many PetSmart and Petco locations host low-cost vaccine clinics where core vaccines cost $15–$25 each, vs. $25–$40 at a full-service vet. Humane societies and shelters also offer low-cost vaccine days. A wellness exam is NOT included at vaccine-only clinics.

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