VetCostCalc

Vaccinations Cost in South Dakota (2026)

South Dakota vet costs are 15% below national avg. See exact vaccinations prices, city breakdowns, and how to save.

Vaccination Costs in South Dakota

Vaccine Per dose
Dog DHPP (combo) $31
Dog Rabies $18
Bordetella (kennel cough) $18
Leptospirosis $16
Cat FVRCP $25
Cat Rabies $15
FeLV (feline leukemia) $18

Vet Cost by City in South Dakota

City Wellness Exam
Sioux Falls $57
Rapid City $56
Aberdeen $53
Brookings $54

Vaccinations Cost in South Dakota — FAQ

How much do dog vaccinations cost in South Dakota?

Annual dog vaccinations in South Dakota cost $90/year in 2026 — 15% below the national average. Core vaccines (DHPP, rabies) are required; non-core vaccines (bordetella, leptospirosis, Lyme) are given based on lifestyle. Puppy series runs $120–$200 total.

How much do cat vaccinations cost in South Dakota?

Annual cat vaccinations in South Dakota average $70/year in 2026. Core cat vaccines include FVRCP and rabies. Indoor cats need fewer vaccines than outdoor cats. Kitten series typically runs $100–$160 total in South Dakota.

Are there low-cost vaccination clinics in South Dakota?

Yes — many PetSmart and Petco locations host low-cost vaccine clinics where core vaccines cost $15–$25 each, vs. $25–$40 at a full-service vet. Humane societies and shelters also offer low-cost vaccine days. A wellness exam is NOT included at vaccine-only clinics.