Vaccinations Cost in South Carolina (2026)
Vet costs in South Carolina are 12% below national avg, so vaccinations prices run lower here too. Exact costs depend on your pet's size, age, and which clinic you use. The breakdown below shows what South Carolina clinics charge for vaccinations in 2026, how each line item compares nationally, and practical ways to save. Low-cost clinics and humane societies can cut some of these prices by half or more.
Vaccination Costs in South Carolina
| Vaccine | Per dose |
|---|---|
| Dog DHPP (combo) | $31 |
| Dog Rabies | $18 |
| Bordetella (kennel cough) | $18 |
| Leptospirosis | $16 |
| Cat FVRCP | $25 |
| Cat Rabies | $15 |
| FeLV (feline leukemia) | $18 |
Vet Cost by City in South Carolina
| City | Wellness Exam |
|---|---|
| Columbia | $58 |
| Charleston | $62 |
| Greenville | $59 |
| Myrtle Beach | $60 |
Vaccinations Cost in South Carolina — FAQ
How much do dog vaccinations cost in South Carolina?
Annual dog vaccinations in South Carolina cost $90/year in 2026 — 12% below the national average. Core vaccines (DHPP, rabies) are required; non-core vaccines (bordetella, leptospirosis, Lyme) are given based on lifestyle. Puppy series runs $120–$200 total.
How much do cat vaccinations cost in South Carolina?
Annual cat vaccinations in South Carolina average $70/year in 2026. Core cat vaccines include FVRCP and rabies. Indoor cats need fewer vaccines than outdoor cats. Kitten series typically runs $100–$160 total in South Carolina.
Are there low-cost vaccination clinics in South Carolina?
Yes — many PetSmart and Petco locations host low-cost vaccine clinics where core vaccines cost $15–$25 each, vs. $25–$40 at a full-service vet. Humane societies and shelters also offer low-cost vaccine days. A wellness exam is NOT included at vaccine-only clinics.
Other Vet Procedure Costs in South Carolina
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Vaccinations Cost in Other States
See full vet cost breakdown for South Carolina: