VetCostCalc

Vaccinations Cost in Missouri (2026)

Vet costs in Missouri are 15% below national avg, so vaccinations prices run lower here too. Exact costs depend on your pet's size, age, and which clinic you use. The breakdown below shows what Missouri clinics charge for vaccinations in 2026, how each line item compares nationally, and practical ways to save. Low-cost clinics and humane societies can cut some of these prices by half or more.

Vaccination Costs in Missouri

Vaccine Per dose
Dog DHPP (combo) $31
Dog Rabies $18
Bordetella (kennel cough) $18
Leptospirosis $16
Cat FVRCP $25
Cat Rabies $15
FeLV (feline leukemia) $18

Vet Cost by City in Missouri

City Wellness Exam
Kansas City $57
St. Louis $59
Springfield $54
Columbia $56

Vaccinations Cost in Missouri — FAQ

How much do dog vaccinations cost in Missouri?

Annual dog vaccinations in Missouri cost $90/year in 2026 — 15% below the national average. Core vaccines (DHPP, rabies) are required; non-core vaccines (bordetella, leptospirosis, Lyme) are given based on lifestyle. Puppy series runs $120–$200 total.

How much do cat vaccinations cost in Missouri?

Annual cat vaccinations in Missouri average $70/year in 2026. Core cat vaccines include FVRCP and rabies. Indoor cats need fewer vaccines than outdoor cats. Kitten series typically runs $100–$160 total in Missouri.

Are there low-cost vaccination clinics in Missouri?

Yes — many PetSmart and Petco locations host low-cost vaccine clinics where core vaccines cost $15–$25 each, vs. $25–$40 at a full-service vet. Humane societies and shelters also offer low-cost vaccine days. A wellness exam is NOT included at vaccine-only clinics.

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