Vaccinations Cost in California (2026)

Vet costs in California are 35% above national avg, so vaccinations prices run higher here too. Exact costs depend on your pet's size, age, and which clinic you use. The breakdown below shows what California clinics charge for vaccinations in 2026, how each line item compares nationally, and practical ways to save. Low-cost clinics and humane societies can cut some of these prices by half or more.

Vaccination Costs in California

Vaccine	Per dose	Notes
Dog DHPP (combo)	$49	Core — distemper, hepatitis, parvo, parainfluenza
Dog Rabies	$28	Core — required by law in most states
Bordetella (kennel cough)	$28	Non-core — required by boarding facilities
Leptospirosis	$25	Non-core — for dogs near water/wildlife
Cat FVRCP	$39	Core — upper respiratory + panleukopenia
Cat Rabies	$24	Core — required by law in most states
FeLV (feline leukemia)	$28	Non-core — recommended for outdoor cats

Vet Cost by City in California

City	Wellness Exam	Notes
San Francisco	$110	Among highest in the US; 70% above national avg
Los Angeles	$90	High demand, high overhead
San Diego	$85	Near state major-metro avg
Sacramento	$75	More affordable than coastal metros
San Jose	$95	Tech corridor wages push prices up

Vaccinations Cost in California — FAQ

How much do dog vaccinations cost in California?

Annual dog vaccinations in California cost $140/year in 2026 — 35% above the national average. Core vaccines (DHPP, rabies) are required; non-core vaccines (bordetella, leptospirosis, Lyme) are given based on lifestyle. Puppy series runs $120–$200 total.

How much do cat vaccinations cost in California?

Annual cat vaccinations in California average $110/year in 2026. Core cat vaccines include FVRCP and rabies. Indoor cats need fewer vaccines than outdoor cats. Kitten series typically runs $100–$160 total in California.

Are there low-cost vaccination clinics in California?

Yes — many PetSmart and Petco locations host low-cost vaccine clinics where core vaccines cost $15–$25 each, vs. $25–$40 at a full-service vet. Humane societies and shelters also offer low-cost vaccine days. A wellness exam is NOT included at vaccine-only clinics.