VetCostCalc

Heartworm Treatment Cost in Mississippi (2026)

Vet costs in Mississippi are 22% below national avg, so heartworm treatment prices run lower here too. Exact costs depend on your pet's size, age, and which clinic you use. The breakdown below shows what Mississippi clinics charge for heartworm treatment in 2026, how each line item compares nationally, and practical ways to save. Low-cost clinics and humane societies can cut some of these prices by half or more.

Vet Cost by City in Mississippi

City Wellness Exam
Jackson $51
Gulfport $49
Hattiesburg $48
Biloxi $49

Heartworm Treatment Cost in Mississippi — FAQ

How much does heartworm treatment cost for a dog in Mississippi?

Heartworm treatment in Mississippi averages $1,170 in 2026 — 22% below the national average. The standard melarsomine protocol (3 injections over 2 months plus pre-treatment bloodwork, X-rays, and strict exercise restriction) typically runs $1,000–$2,500 total. Annual heartworm prevention costs $90 and is far less expensive.

Is there a cheaper heartworm treatment option in Mississippi?

The 'slow kill' method (monthly ivermectin without melarsomine) is cheaper but takes 1–2 years, doesn't kill adult worms directly, and is no longer recommended by the American Heartworm Society due to resistance concerns. The standard melarsomine protocol at $1,170 in Mississippi is the only AHS-approved treatment. Humane societies and veterinary schools sometimes offer discounted treatment.

What happens if heartworms are left untreated in Mississippi?

Untreated heartworm disease is fatal. Adult worms grow up to 12 inches long inside the heart and pulmonary arteries, causing progressive heart and lung damage. Dogs with heavy worm burdens develop congestive heart failure within 1–3 years. In Mississippi, heartworm prevention costs $90/year — about 8% of what treatment costs. Prevention is the clear choice.

Heartworm Treatment Cost in Other States